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A review on the role of NCK1 Antisense RNA 1 (NCK1-AS1) in diverse disorders

GND
124970715312497071531249707153
ORCID
0000-0001-8381-0591
Zugehörigkeit
Institute of Human Genetics, Jena University Hospital
Taheri, Mohammad;
Zugehörigkeit
Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Askari, Arian;
Zugehörigkeit
School of Pharmacy, University of California, San Francisco, USA
Behzad Moghadam, Kimia;
Zugehörigkeit
Department of Clinical Analysis, College of Pharmacy, Hawler Medical University, Kurdistan Region, Erbil, Iraq
Hussen, Bashdar Mahmud;
Zugehörigkeit
Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Ghafouri-Fard, Soudeh;
Zugehörigkeit
Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Kiani, Arda

NCK1 Antisense RNA 1 (NCK1-AS1), alternatively named as NCK1-DT, is a long non-coding RNA (lncRNA) with important roles in the carcinogenesis. Multiple studies verified its oncogenic role in different types of cancer, including gastric cancer, non-small cell lung cancer, glioma, prostate cancer and cervical cancer. NCK1-AS1 functions as a sponge for several microRNAs, including miR-137, miR-22-3p, miR-526b-5p, miR-512-5p, miR-138-2-3p and miR-6857. In this review we present an outline of NCK1-AS1 function in malignant conditions as well as atherosclerosis.

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Einordnung

Erschienen in:
Pathology, research and practice
Bd. 245 (05.2023)Art.-Nr.:154451
Band:
245
Datum der Veröffentlichung:
05.2023
URN:
urn:nbn:de:gbv:27-dbt-20240408-153918-009
DOI:
10.1016/j.prp.2023.154451
Sonstiger Identifikator (pubmed):
37028107
Sprache:
Englisch
Ressourcentyp:
Text
Umfang:
7 Seiten
Verlag:
Elsevier BV
Schlagwörter:
Cell Line, Tumor; Humans; Glioma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; RNA, Antisense; MicroRNAs; Cell Proliferation; Gene Expression Regulation, Neoplastic; Male; RNA, Long Noncoding; Cancer; microRNAs; Lncrna; Nck1-as1
DDC-Sachgruppe der DNB:
610 Medizin, Gesundheit
Einrichtung:
Friedrich-Schiller-Universität Jena, Medizinische Fakultät
Anmerkung:
Zweitveröffentlichung

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