We study spectral problems for two-dimensional integral system with two given non-decreasing functions R, W on an interval [0, b) which is a generalization of the Krein string. Associated to this system are the maximal linear relation Tmax and the minimal linear relation Tmin in the space L2(dW) which are connected by Tmax=T*min. It is shown that the limit point condition at b for this system is equivalent to the strong limit point condition for the linear relation Tmax. In the limit circle case the Evans-Everitt condition is proved to hold on a subspace T*N of Tmax characterized by the Neumann boundary condition at b. The notion of the principal Titchmarsh-Weyl coefficient of this integral system is introduced. Boundary triple for the linear relation Tmax in the limit point case (and for T*N in the limit circle case) is constructed and it is shown that the corresponding Weyl function coincides with the principal Titchmarsh-Weyl coefficient of the integral system. The notion of the dual integral system is introduced by reversing the order of R and W and the formula relating the principal Titchmarsh-Weyl coefficients of the direct and the dual integral systems is proved. For every integral system with the principal Titchmarsh-Weyl coefficients q a canonical system is constructed so that its Titchmarsh-Weyl coefficient Q is the unwrapping transform of q: Q(z)=zq(z2).